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020 _a1555812546
040 _aDNLM/DLC
_dDLC
082 0 4 _a615.329
_221
099 _a25-W14
100 1 _aWalsh, Christopher
245 0 2 _aAntibiotics :
_bactions, origins, resistance
_cby Christopher Walsh.
260 _aWashington, D.C. :
_bASM Press,
_cc2003.
300 _ax, 335 p. :
_bil. (algunas col.) ;
_c26 cm.
504 _aIncluye referencias bibliográficas (p. 297-328) e índice.
505 0 _aAntibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
650 7 _aAntibióticos
_2Spines
650 7 _aResistencia microbiana de los medicamentos
_2Spines
650 7 _aFarmacología
_2Spines
929 _aCOMPRA
_bIntelecnia
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929 _aCOMPRA
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929 _aCOMPRA
_bIntelecnia
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942 _cLIB
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999 _c17864
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